Bufo Alvarius: fusion with the totality

It is an experience of fusion with the Totality, of Unity, which allows us the possibility of recovering the memory of the immensity of what we really Are; the borders of identity disappear like a doll of salt that dissolves in the ocean of consciousness of Infinite Love, producing a massive release of accumulated stress and repressed emotions.

It is an experience of fusion with the Totality, of Unity, which allows us the possibility of recovering the memory of the immensity of what we really Are; the borders of identity disappear like a doll of salt that dissolves in the ocean of consciousness of Infinite Love, producing a massive release of accumulated stress and repressed emotions. The climax of the experience arrives 3 minutes after taking it, then a state of immense peace and serenity occurs until the connection with the ego gradually returns, recovering the usual sensation.

The medicine extracted from the glands of the toad Bufo Alvarius of the Sonoran desert (Mexico) is considered the most powerful entheogen that exists. Its form of consumption is inhaling in a pipe the smoke that is produced by burning the dry secretions that result from the extraction; It should be emphasized that during the collection of the medicine, the toad does not suffer any damage when milked and is returned to its natural habitat. These toads only come out three months a year and it is the only species of toad in the world that has this substance.

The experience lasts between 15 and 20 minutes but whoever is living it loses the sense of time experiencing a dizzying feeling of eternity, infinity and unity with all existence; during the experience it is also possible to go through moments of great anguish that are the prelude to the encounter with the divine, these moments prior to ecstasy and the total oceanic feeling of communion with oneself and life have to do with the feeling of being thrown into the void At great speed, the transitory but total dissolution of the ego is the launch pad of the Being towards an unimaginable connection with the Whole. Great courage is required to live such an experience, those who cross the threshold of the temporary death of the ego are dispossessed of the veil of the illusion of separateness to be fully immersed in the peak experience of unity. As there are no divisions in perception, the memory of where we come from and where we are going is fully recovered.

It is necessary to clarify that it is not about vague sensations or subtle feelings, truly one enters into the perception of being with the whole: "YOU ARE the divinity, YOU ARE everything...", so it is surely the most powerful and profound experience that can experience a human being.

It is an encounter with the absolute, the mystical experience par excellence where the observer merges with the observed and consciousness is aware of itself, it is a Gestalt change, in everyday life we ​​can experience the divine from the human, but with the toad we experience the human from the divine, we look for an instant through the eyes of God or Creation fused in the totality of the present moment.

It is shared individually, medicine is given one by one, although the development of the process is carried out in a group. The person requires all the attention and care while they are navigating in the immense trance that involves merging with the Universe.

The possible "effect" of bufo alvarius is to understand that You Are, We Are in Unity the Cause of Everything. Creation complete and at the same time eternally expansive and full.

After the experience there must be an integration session.

With the bufo alvarius you have the possibility of becoming directly in the Cosmic Consciousness, that is to say, any question or question before the overwhelming Absolute Love disappears before your eyes. That is why I affirm without any fear of being labeled as radical, dupe or apologetic that it is unlikely or impossible for a human being to experience that experience on their own. This does not mean that you cannot understand what a human being lives in his life after having smoked it, but the experience in itself is such a dissolution of the ego that unless divine grace spontaneously visits you, you will rarely be able to live something like that with some rigorous method of meditation. What I write I support not only with my experience but with that of hundreds of meditators who have given me their testimony of it.

I invite you and summon the courageous man and woman in you to make the leap into immensity so that we can dance together the dance of the blessed, the grace of the derisory and the feast of the worthy who open themselves to receive without any I repair the infinite gift of feeling eternally happy.

BUFO ALVARIUS IS NOT A HALLUCINOGEN. IT IS AN ENTHEOGEN THAT HAS A DISALLUCINOGENIC EFFECT ON THE PERSON

In the peak experience of unity generated by the buffo alvarius, there are no hallucinations and there is no such thing as a hallucinatory, since it is a non-dual experience. It is a miracle that there is something in nature that allows you to live an experience of momentary illumination and that existence has decided to hide this key on the back of an amphibian.

It is classified as an entheogen, which connects you with entheos (God, in Greek).

The apotheosis of the experience is the total unity, the samadhi, for which nothing is experienced as something fragmented, this means that the veil of maya dissolves and with it the illusion or hallucination of separateness, in this sense it is that cataloged as hallucinogen, the ego dissolves and disappears with it the leprous perception of the world full of lack; then an immeasurable fullness is manifested in which we dissolve like a doll of salt in the ocean of existence and where the idea of ​​error and guilt are completely eradicated.

This confirms what Osho said: "life is not a dream, the dream is you"

On the other hand, and given the great misinformation that is appearing in the media, there is no reported case of death that has the direct cause of having smoked the Bufo Alvarius medicine, however all those who have smoked it have died and been reborn. Regarding the death of Jose Luis Abad after supposedly smoking "bufo alvarius" given to him by Nacho Vidal, this information is also false, since the cause of this death was not the bufo alvarius but the mixture of cocaine that he had taken, what he did not warn, along with what he smoked, which is not yet clear if it was bufo alvarius or synthetic 5-meo-dmt given Nacho Vidal's refusal to give the substance extracted from the toads, for reasons of "ecological ethics" of not damage or stress the toad. Both synthetic 5meo dmt and bufo alvarius are safe substances, although in the case of the synthetic the doses that must be given are much lower. There are not even a dozen deaths reported worldwide where bufo alvarius was involved, most or all of them due to concealment of information by the participant (they do not say that they are under the influence of drugs), negligence of the facilitator (give an excessive dose, the appropriate dose in bufo is between 35 and 75 mg and in the case of synthetic 5 meo dmt between 5 and 25 mg), or because they have smoked it alone (an American girl drowned in her bathtub when she went to back for smoking 5meodmt alone and no one holding her), or as in the case of a Portuguese man who died from a clot that he already had in his leg and that could have moved in another intense situation such as playing sports. An overdose of bufo alvarius is not possible since the alveolar capacity of our lungs is not sufficient to inhale enough of the secretion to do so. This is comprehensively explained by doctor Gerardo Ruben Saandoval:

It is also being classified as a drug when a drug is something that is used to evade reality, in this sense, if someone intends to smoke bufo alvarius with the purpose of escaping, I do not recommend it because there is no possibility of fleeing from The Encounter with the absolute glory in which it ends after crossing the threshold of fear and forgetfulness of what we are not.

With ayahuasca your consciousness expands however with bufo alvarius you become The Consciousness and there is that heaven of the spirit this discussion is laughable, you have arrived...

When you come back from the experience you can see how the character is restructured and witness the appearance of that ridiculous and absurd voice in the head that comments everything. However, before you did not know that that voice could disappear, you did not know that it was unreal, now you lived an experience where it did not have power or where it did not exist and you are able to place yourself internally in a place of disidentification where you can experience the peace of simply Being.

The exciting history of bufo alvarius medicine, who discovered it and how did it spread? : https://www.escuelafloresiendo.com/la-apasionante-historia-de-la-medicina-del-sapo-bufo-alvarius-quien-la-descubrio-como-se-expandio-por-el-mundo/

THERAPEUTIC POTENTIAL OF BUFO ALVARIUS

(5-MEO-DMT): CLINICAL AND SCIENTIFIC EVIDENCE PUBLISHED IN MEDICAL ARTICLES

"Prospective observational studies on naturalistic use of synthetic 5-MeO-DMT and 5-MeO-DMT-containing toad secretion in healthy volunteers have demonstrated immediate and long-lasting improvements in self-reported ratings of depression, anxiety, stress, life-related abilities." mindfulness and satisfaction with life, after just one inhalation of the substance (Uthaug et al., 2019 ; Uthaug, Lancelotta, Szabo, et al., 2020 ). The first prospective study with 5-MeO-DMT (Uthaug et al., 2019) demonstrated that compared to baseline, participants (n = 42) reported reductions in depression, anxiety, and stress, as well as increases in related abilities. with mindfulness and life satisfaction, 24 h after ingestion of toad venom containing 5-MeO-DMT. Such improvements in mood, mindfulness-related abilities, and life satisfaction were found to persist up to 4 weeks after intake. Furthermore, participants who experienced higher levels of ego dissolution were found to report higher levels of life satisfaction and lower levels of depression and stress 24 h after the drug experience. A follow-up study by the same group (Uthaug, Lancelotta, Szabo, et al., 2020) demonstrated that mindfulness-related abilities improved and feelings of depression were reduced immediately after 5-MeO-DMT intake. synthetic compared to baseline (N = 11). Seven days after ingestion, mindfulness-related abilities continued to improve and feelings of anxiety and stress were significantly reduced compared to baseline (Uthaug, Lancelotta, Szabo, et al., 2020). Again, it was found that the more acute the experience of ego dissolution, the greater the decrease in feelings of depression, anxiety and stress, and the greater the increase in abilities related to mindfulness, both directly after the session as in the 7-day follow-up (Uthaug, Lancelotta, Szabo, et al., 2020). Taken together, the results of these two prospective studies demonstrate fast-acting, and in some cases immediate, improvements in mood in self-declared healthy volunteers who ingested the substance in a naturalistic setting. Importantly, these studies also suggest a relationship between the strength of the acute psychedelic experience and the magnitude of persistent mood swings.

Additional observational studies have reported reductions in symptomatology of a variety of different psychiatric disorders diagnosed after ingestion of 5-MeO-DMT. Davis et al. ( 2018 ) employed a cross-sectional survey to characterize usage patterns and evaluate potential risks and benefits associated with 5-MeO-DMT use. Of respondents who indicated they had been diagnosed with a psychiatric disorder, marked improvements were reported in the following conditions: post-traumatic stress disorder (79%), depression (77%), anxiety (69%), substance use problems (63%). %) and obsessive-compulsive disorder (53%), with a notably small proportion (2-10%) reporting worsening of these conditions. In a separate cross-sectional survey, the same group (Davis et al., 2019) demonstrated similar reports of improvements in depression and anxiety conditions among respondents after use of 5-MeO-DMT in a group setting. That is, the authors demonstrated that of those with depression (n = 149), 80% reported an improvement in their conditions after the use of 5-MeO-DMT, while 17% reported no change in depression and mood. 3% reported worsening of their depression. In those who had anxiety (n=173), 79% reported an improvement in their condition after the use of 5-MeO-DMT, while 19% reported no change in anxiety and 2% reported a worsening of your anxiety. Similar to observational studies in healthy participants, Davis and colleagues (Davis et al., 2019) found that the stronger the mystical experience, the higher the spiritual meaning and personal meaning ratings of the acute 5-MeO-DMT experience. , the greater the improvements reported in depression and anxiety. The authors further noted that, of the entire sample, only 7 people reported using 5-MeO-DMT specifically to relieve their depression or anxiety, highlighting that the improvements reported by the majority of respondents were unintentional.

Davis and colleagues (Davis et al., 2018) examined use patterns, motivations for use, and subjective experiences associated with 5-MeO-DMT use using a web-based retrospective survey (N = 515). . The findings revealed that respondents consumed 5-MeO-DMT infrequently, less than once a year and less than four times in a lifetime, primarily for spiritual exploration. The majority (90%) reported moderate to strong mystical-type experiences (ineffability, timelessness, awe/wonder, experience of pure being/consciousness) and relatively fewer (37%) experienced challenging experiences. Less than half (39%) reported repeated use during the same session, and very few reported drug craving/desire (8%), legal (1%), medical (1%), or psychiatric (1%) related problems with the use.

A recent review of 20 studies evaluating the clinical response to psychedelics in patients with an addictive disorder, treatment-resistant depression, and obsessive-compulsive disorder provided further support and concluded that the main predictor of a response to a psychedelic is the intensity of the acute psychedelic experience (Romeo et al., 2021). This conclusion also seems to be in line with the results of the 2 observational studies on 5-MeO-DMT (Uthaug, Lancelotta, Szabo, et al., 2020; Uthaug et al., 2019) reported previously, in which the Higher intensities of the 5-MeO-DMT experience, that is, higher ratings of the ego dissolution experience, were associated with stronger long-term improvements in mental health outcomes.

Findings from studies in self-proclaimed healthy volunteers suggest immediate and lasting improvements in self-reported feelings of depression, anxiety, stress, and life satisfaction, after a single inhalation of the substance (Uthaug, Lancelotta, Szabo, et al., 2020 ; Uthaug et al., 2019 ). Additionally, reductions in diagnosed depression and anxiety symptomatology have been reported (Davis et al., 2018 ; Davis et al., 2019 ), as well as a variety of other psychiatric disorders such as PTSD, substance use problems and obsessive-compulsive disorder (Davis et al., 2018) after 5-MeO-DMT ingestion. Although limited, studies offer converging evidence of 5-MeO-DMT's potential ability to provide fast-acting and potentially immediate therapeutic relief for depression, anxiety, and stress-related disorders (such as PTSD) in particular.

The main difference between Bufo alvarius toad venom and synthetic 5-MeO-DMT is that the former contains a range of pharmacologically active compounds in addition to 5-MeO-DMT. These include cardioactive agents such as bufagins (i.e., bufandienolides), catecholamines, such as epinephrine and norepinephrine, indolealkylamines, such as bufothionine, serotonin, cinobufotenin, bufotenin, and dehydrobufotenin, and non-cardiac sterols, such as cholesterol, provitamin D, gamma sitosterol, and ergosterol (Erspamer et al., 1965 ; Erspamer et al., 1967 ; Chen and Kovarikova, 1967 ). It is currently unknown whether any of these additional compounds synergistically modulate the effects of 5-MeO-DMT in ways that would be relevant for therapeutic applications. Research on the “entourage” effects of toad venom would be of fundamental scientific interest, since its pharmacological constellation can optimize therapeutic results. It is true that the mental health improvements that have been associated with 5-MeO-DMT were similar for users of toad venom and synthetic versions of 5-MeO-DMT, suggesting that 5-MeO-DMT is the main compound with therapeutic potential (Uthaug, Lancelotta, Szabo, et al., 2020 ; Uthaug et al., 2019 ; Davis et al., 2019 ).»

Scientific source:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314805/

SIX SPANISH HOSPITALS IN BARCELONA, MADRID, OVIEDO AND SALAMANCA ARE CONDUCTING CLINICAL TRIALS WITH 5-MEO-DMT FROM THE BUFO ALVARIUS TOAD TO TREAT DEPRESSION:

These are the following hospitals:

Barcelona:

-Parc Sanitari Sant Joan de Deu HD Numancia

-Clinic Hospital of Barcelona

-Hospital del Mar

Madrid:

-HM Hospital Research Foundation

Oviedo:

-La Corredoria Mental Health Center

Salamanca:

-San Juan Health Center

«At a time when mental health is more important than ever, Madrid is at the forefront of medical innovation with the launch of the first clinical trial with psychedelics aimed at people suffering from treatment-resistant depression: https://clinicaltrials.gov/study/NCT05870540?tab=table

Together with Barcelona, ​​Salamanca and Oviedo, Madrid contributes to research into the therapeutic use of 5-meo-DMT (active ingredient in SAPO BUFO ALVARIUS) in the trial of the psychedelic pharmaceutical company Beckley Psytech ( https://www.beckleypsytech.com/) representing a ray of hope for those who have not found relief in conventional treatments. Initial results have been encouraging, with 55% of patients experiencing a rapid antidepressant response within a day of administration, and with effects lasting up to 85 days in some cases.

Participants will receive a single dose of the compound BPL-003 (a proprietary presentation of 5-meo-dmt), administered intranasally, and will be carefully monitored through regular clinical and psychiatric evaluations. In addition, they will be offered psychological support before, during and after the administration of the treatment, underlining the commitment not only to the effectiveness of the treatment, but also to the safety and well-being of the participants.

At a time when mental health is more important than ever, Madrid is at the forefront of medical innovation with the launch of the first clinical trial with psychedelics aimed at people suffering from treatment-resistant depression. Together with Barcelona, ​​Salamanca and Oviedo, Madrid contributes to research into the therapeutic use of 5-meo-DMT in the trial of the psychedelic pharmaceutical company Beckley Psytech, representing a ray of hope for those who have not found relief in conventional treatments. Initial results have been encouraging, with 55% of patients experiencing a rapid antidepressant response within a day of administration, and with effects lasting up to 85 days in some cases.

Participants will receive a single dose of the BPL-003 compound, administered intranasally, and will be carefully monitored through regular clinical and psychiatric evaluations. In addition, they will be offered psychological support before, during and after the administration of the treatment, underlining the commitment not only to the effectiveness of the treatment, but also to the safety and well-being of the participants.

The trial, which is currently being carried out simultaneously in several countries such as the United States, Germany, Poland and Australia, will admit the last participants in early October 2024. Those interested can contact the different centers through this link: https://inawe.life/investigacion/

This clinical trial is not only significant because it offers a potential new treatment for resistant depression, but also represents an important step towards changing the perception and management of mental illness, and towards facilitating access to assisted therapies. psychedelics, opening the door to this type of treatments in the future.

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